In recent years there has been a growing recognition of the impact that mining practices have on the efficiency of mineral processing operations. Head grade, dilution, particle size distribution and their variability are known to have a significant effect on the throughput and recovery achieved in mineral processing plants. Improved process monitoring and modelling have provided the opportunity to identify and quantify some of these impacts and to define very significant incentives to optimise the overall operation from the mining face through subsequent comminution and processing. The Julius Kruttschnitt Mineral Research Centre has been undertaking research to optimise Mine to Mill' performance through a major AMIRA research project and through individual research contracts with mining companies. This work has resulted in a broad range of field and laboratory experience in terms of both the challenges and the opportunities encountered when tailoring blasting operations to suit the overall Mine to Mill' production chain. This paper describes the objectives of Mine to Mill' blasting to optimise the system of rock breakage involved in the blasting, crushing and SAG milling of hard, brittle ores. The design of such blasts falls outside the conventional envelope of experience for most engineers and requires the consideration of some critical factors if the objectives of such blast are to be met and some of the potential problems are to be avoided. Experience to-date has also found that the quality of implementation is critical to the success of Mine to Mill' blasts.