It is well documented that drill and blast outcomes affect the downstream mining processes of loading, hauling, crushing and grinding but it can also significantly impact on mine profitability via dilution, recovery percentage, lump generation (iron ore), fines generation (coal, iron ore), coal loss and final wall stability. Drill and blast must therefore be optimised to improve the overall profitability via positively impacting on productivity and saleable product generation. It is however, difficult to achieve this because of the complexity of the number of parameters that must be integrated and managed across the entire mine value chain, ie the concept of Mine to Mill'. This paper highlights, via a simple case study, the need to have a mine's drill and blast system both in control (so that it is predictable to a high degree) and with minimal variability (so the design actually makes it into the field). This type of management control is essential prior to optimisation work being undertaken. The Team Approach' is discussed to illustrate the methodology of achieving drill and blast optimisation. A case study is presented to illustrate the potential benefits of this approach which in this mine represented a 27 per cent reduction in powder factor with the downstream functions achieving higher productivity with the same or reduced maintenance costs. It is essential for Australian mine's to implement the appropriate management strategies and experienced personnel placement to ensure that their mine's drill and blast system is correctly managed to facilitate the optimisation of profit. Without this, the Australian mining sector will become increasingly uncompetitive.