A number of mines in Australia have experienced premature detonations caused by bulk explosives reacting with the rock type being blasted. Premature detonations are extremely high risk events as they are unplanned, occurring at any place, at any time, potentially resulting in high loss (personnel and equipment). Many Australian mines have also experienced spontaneous combustion where spilt explosive reacts vigorously with the rock type. Premature detonation in these cases does not occur due to the lack of confinement and the volume of explosive present, but these reactions could impinge on the surface initiation system and provide an early warning of future premature detonations. The explosive ground reactivity phenomena is not restricted to Australia with similar incidents being reported in North and South America, South Africa, China and South East Asia. All reported incidents have two common denominators, being the presence of sulphide rock types and nitrate based explosives. Both premature detonation and spontaneous combustion result from the same series of reactions of partially weathered sulphides that ultimately result in the violent decomposition of the ammonium nitrate based explosive. A number of relatively easily observable indicators can be used to assess a particular minesite's potential for explosive ground reactivity. The presence of two or more of these indicators means that minesite personnel should contact their explosives manufacturer for assistance in determining if a problem exists and if so then developing strategies to overcome the situation. The paper describes the indicators as well as discussing, via a case study, the holistic approach required to efficiently develop a relevant Safe and Efficient Blasting Procedure' to deal with explosive ground reactivity problems.