A better connection between laboratory- and pilot-scale test results, and heap bioleaching performance can be achieved by generating reliable information on the fundamental microbial, chemical and physical processes that occur in heaps and incorporating this information into a comprehensive and robust model. More efficient heap bioleaching, particularly of chalcopyrite, has the potential to add value to the mining industry as well as deliver attractive environmental and social benefits to the communities within which those companies operate._x000D_
The results of fundamental chemical and microbiological studies of the leaching mechanism, the temperature dependence of chalcopyrite bioleaching, and the optimisation of leaching conditions are described with examples from full-scale heaps. The development and application of a number of novel techniques and tools has assisted our understanding of heap subprocesses mineralogy, hydrology, chemistry and microbiology. The heap bioleaching model HeapSim, which embodies a large number of effects not previously accounted for in other models, continues to be refined and has been applied successfully to the study of several heap bioleach systems.