New technologies can easily take around ten years to commercialise. Strong research support is needed in parallel with the process of innovation and commercialisation, in building a deeper understanding of the underpinning physicochemical and hydrodynamic forces that deliver the separations, in achieving improvements, in the deployment of a new technology, and in expanding the innovation platform to create new IP. External investment beyond the research, derived from the genuine value proposition of transformational change, funds the pathway for traversing the so-called Valley of Death.