IGO Ltd’s (IGO) Nova Operation (Nova) is 160 km east-north-east of the town of Norseman in Western Australia (WA). Discovered by Sirius Resources NL (Sirius) in 2012 and acquired by IGO in 2015, the Nova-Bollinger Deposit (Nova-Bollinger) occurs within the Fraser Zone of the Albany_x0002_Fraser Orogen. Nova-Bollinger is a complex nickel-copper-cobalt (Ni-Cu-Co) magmatic intrusive sulfide deposit, which is characterised by high-grade folded and undulating breccia lodes that host the bulk of the payable metals. Significant sulfide mineralisation is also found in several magmatic intrusive styles including net-textured, disseminated and blebby styles. A smaller but material volume of sulfides has also been remobilised into the deposit’s footwall rocks as ‘stringer’ bands in metasediments, or as discrete massive sulfide lenses. When interpolating Mineral Resource estimate (MRE) block grades in the presence of locally varying grade connectivity trends, such as folds or undulations, the sample search neighbourhood, which is used to identify the composites subset that is used for each block estimate, should be oriented to match the local trends. In theory, the most robust method of estimation where locally varying angles (LVAs) are applied to search neighbourhoods, are techniques where the composites and the blocks to be estimated are transformed to an unfolded coordinate system (UCS). However, UCS methods can be tedious to implement and require subjective decisions to be made that cannot always be fully defended. An alternative LVA method commonly used in the industry is dynamic anisotropy (DA), which is much simpler to implement and is often assumed (but not that often demonstrated) to result in similar results to UCS-style estimation. In 2018, Nova’s Mine Geology team (MGT) estimated the grades and density of the Nova-Bollinger MRE using the UCS approach. For the 2020 MRE update, Nova’s MGT tested and compared the USC grade interpolation method with the DA approach. As applied to the Nova-Bollinger’s 2020 MRE, the comparison, advantages and disadvantages of the two estimation methods are the subject of this paper