Tailings are generally deposited on or near to the mine sites, occupying the site area, and being an economic burden for mining companies. Tailings can cause several environmental impacts, such as leaking toxic substances and contaminating underground water, emitting greenhouse gases, and damaging natural bodies and wildlife. Geopolymerisation of mine waste effectively transforms mine waste into more valuable, environmentally friendly products. Geopolymers are inorganic aluminosilicate materials that are widely applied in the construction industry (Araya, Kraslawski and Cisternas, 2020). The high performance and the low-CO2 emission of geopolymers make this type of material potentially more desirable than ordinary cement, given that manufacturing one ton of traditional cement generates approximately 0.8 tons of CO2. This process is seen as a promising method for repurposing tailings and reducing the environmental impact of mining waste. However, the environmental impact of geopolymer production is not sufficiently comprehended (Mazzinghy et al, 2022). Moreover, geopolymerisation of mine waste can offer several economic benefits, including reduced waste management costs (Amari et al, 2019; He et al, 2022), reduced raw material costs, and potentially lower production costs. However, there are several challenges that need to be addressed to ensure the economic feasibility of the process. This study aims to demonstrate the potential environmental impacts of geopolymer concrete produced using mine wastes and industrial by-products such as blast furnace slag (BFS). For this, a comparative cradle-to-gate life cycle assessment (LCA) methodology was conducted on different geopolymer mix designs, and the greenhouse gas (GHG) emissions results were compared to the ordinary cement. LCA can be used to evaluate the environmental impact of geopolymerisation of mine wastes in various ways. One important impact category is GHG gas emissions, which contribute to climate change and is the focus of this study. Another aim of this study is to evaluate the economic feasibility of the geopolymerisation of mine wastes via economic analysis (EA) to identify the key economic factors and trade-offs associated with repurposing mine wastes through geopolymerisation.