The Deseado Massif volcanic and epithermal province is located in the northern portion of the Santa Cruz province, southern Argentinean Patagonia (Fig. 1). It is a 60,000 km2 geological unit recording an extensive Middle to Late Jurassic bimodal calc-alkaline volcanic event demarcated by the Baha Laura Complex (BLC), consisting of andesites, intermediate to acidic primary volcanics, and late acidic reworked volcanic rocks (Guido & Campbell, 2011).The metallogenical province hosts economic gold and silver-bearing, mainly low sulphidation, epithermal deposits within the BLC, with 10 active mines, and one more recently closed, together with four more advanced projects with 43-101 reports on their published resources (Fig. 1). CITATION: Guido, D M and Campbell, K A, 2019. Deseado Massif hot spring deposits (Late Jurassic, Patagonia, Argentina) and their association with epithermal systems, in Proceedings PACRIM 2019, pp 304306 (The Australasian Institute of Mining and Metallurgy: Melbourne).