The development, piloting and engineering design of an innovative water treatment system for process water produced by a uranium mine mill are described. The process incorporates lime/carbonate softening (Stage 1), reverse osmosis (Stage 2) and biopolishing (Stage 3) to produce water of quality suitable for release to the receiving environment. Comprehensive performance data are presented for each stage. The unique features of the proposed process are: recycle of the lime/CO2 softening sludge to the uranium mill as a neutralant; potential use of power station off-gas for carbonation; and the potential recovery and recycle of ammonia from the RO reject stream.