The effects of process variables such as solution chemistry, flocculent type and dosage, intensity and duration of mixing, and solids type and concentration, on the performance of flocculation/clarification/thickening processes are described. System response is evaluated in terms of the specific effects on floc settling, supernatant clarity and sediment compressibility. The implications of these results with respect to industrial practice are discussed and general guidelines for direct application to plant design and operation are suggested.